Condition Solutions

Haemoglobinopathy Patient Management

Digital patient management software built specifically for haemoglobinopathy services — connecting patients and clinical teams to improve outcomes and reduce the burden of reactive, crisis-led care.

Connected Care for Haemoglobinopathy Services

Haemoglobinopathies are a group of inherited blood disorders affecting haemoglobin — the protein in red blood cells that carries oxygen. The two most clinically significant conditions in the UK are sickle cell disease and thalassaemia.

Both conditions share a common set of clinical management challenges: fragmented data, poor medication adherence, reactive rather than proactive care, and an NHS infrastructure that was not designed to support life-long condition management at scale.

ProtoFlex addresses these challenges head-on — with condition-specific digital pathways that connect patients, carers and specialist clinical teams into a single, coordinated care model.

Read our TechUK guest blog ↗

17,000+ people with SCD

The UK has the largest population of sickle cell patients of any non-endemic country in Europe

£50m annual NHS spend

Driven largely by avoidable A&E admissions and unplanned bed days for sickle cell crises alone

50–70% of crises are preventable

With better medication adherence and proactive clinical monitoring — the core of what ProtoFlex delivers

Clinical input from NHS trusts

Clinical leads, community teams and key stakeholders from a number of NHS trusts have shaped the design

Dedicated Models for Each Condition

Each haemoglobinopathy has distinct clinical needs. ProtoFlex delivers condition-specific pathway models that reflect real clinical workflows — not generic templates.

Available Now

Sickle Cell Disease

A fully developed, NHS co-designed patient management solution for sickle cell disease — reducing A&E admissions through proactive monitoring, improving medication adherence and freeing clinical time from data administration.

  • Unified patient data view — no more manual aggregation
  • Real-time monitoring with configurable crisis alerts
  • Patient portal for adherence support & self-management
  • Annual review & haemoglobinopathy registry submission
In Development

Thalassaemia

A dedicated patient management solution for thalassaemia is currently in active development — built on the same proven platform and clinical pathway models as our sickle cell solution, tailored for the distinct clinical needs of thalassaemia care.

  • Transfusion programme tracking & scheduling
  • Iron chelation adherence monitoring
  • Annual review & registry submission support
  • Paediatric to adult transition pathways (planned)

Treating other haemoglobin disorders? ProtoFlex's generic clinical pathway model can be adapted for any haemoglobinopathy — from HbSC disease to haemoglobin E disorders.

Talk to us about your condition

Proactive, Connected, Configurable

Three principles that run through every ProtoFlex haemoglobinopathy solution — reflecting what clinical teams and patients told us they need most.

Proactive

Configurable monitoring thresholds surface deteriorating patients before a crisis develops. Real-time cohort visibility means your team can intervene early — not reactively in A&E.

Connected

Patients, carers and clinical teams all contributing to a single, unified care record. ProtoFlex Connect links to existing NHS systems — no data silos, no manual reconciliation.

Configurable

Clinical leads configure workflows, alert logic and patient-facing content to their local protocols — no developer required. Your service, your rules.

Developed With NHS Clinical Teams

ProtoFlex haemoglobinopathy solutions have been shaped by clinical leads, community teams and key stakeholders from a number of NHS trusts, who have generously volunteered their time and insights to help develop a model that spans the different strands of healthcare — ensuring workflows reflect real clinical practice, not assumptions.

NHS Trust Clinical Leads

Specialist haematology consultants providing design input on adult SCD pathways, clinical governance and data requirements

Community Teams

Nurses, care coordinators and allied health professionals contributing insight into patient management and care coordination across settings

Paediatric & Transition Specialists

Paediatric clinical input ensuring the platform supports paediatric care and the transition to adult services

Request a demonstration Explore the platform

Interested in how ProtoFlex integrates with your existing systems? Read about NHS interoperability or our companion protocols approach.

Contact Us

Let's Talk About Your Service

If you'd like to discuss how ProtoFlex can help your organisation, fill in our contact form and a member of the team will get in touch.

Our Location

C/O Ampa Holdings Llp, Level 19, The Shard, 32 London Bridge Street, London SE1 9SG

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