Condition Solution — Haemoglobinopathy

Thalassaemia Patient Management

Digital patient management software for thalassaemia, built on ProtoFlex's proven haemoglobinopathy platform. Currently in development — register your interest to shape the solution.

In Development — Coming Soon

The ProtoFlex thalassaemia solution is currently in active development. If you are a haematology or thalassaemia clinical lead interested in shaping this solution, we'd love to hear from you. Early adopters will have the opportunity to contribute to co-design.

What is Thalassaemia?

Thalassaemia is an inherited blood disorder affecting haemoglobin production, causing the body to make fewer healthy red blood cells than normal. It is closely related to sickle cell disease within the wider haemoglobinopathy spectrum.

There are two main types — alpha thalassaemia and beta thalassaemia — with severity ranging from the thalassaemia trait (carrier) through to transfusion-dependent thalassaemia major. Like sickle cell disease, it predominantly affects people of South Asian, Mediterranean, Middle Eastern and African heritage.

Patients with thalassaemia major require regular blood transfusions and iron chelation therapy — demanding close clinical monitoring, strong patient engagement and coordination across specialist teams. These are the same core challenges ProtoFlex has addressed in sickle cell disease.

Transfusion programme tracking

Scheduling, records and patient communication for regular transfusion cycles

Iron chelation adherence monitoring

Patient-reported outcomes and alerts to support treatment adherence

Annual review & registry submission

Haemoglobinopathy registry support and audit tools

Shared-care coordination

Connecting specialist centres with local services for complex patients

Paediatric to adult transition pathways

Planned — subject to co-design input

Built on Our Proven Haemoglobinopathy Platform

The thalassaemia solution will be built on the same platform and clinical pathway models that underpin our sickle cell disease solution — already co-designed with leading NHS haemoglobinopathy services.

ProtoFlex can also run alongside your existing systems as a companion protocol. Learn more about our NHS interoperability approach.

Be Part of the Co-Design

If you are a thalassaemia clinical lead, service manager or patient advocate and would like to contribute to the design of this solution, we would love to hear from you. Early conversations shape better products.

Register your interest

In the meantime, read about our sickle cell solution — the platform on which thalassaemia will be built.

Sickle Cell Disease patient management →

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If you'd like to discuss how ProtoFlex can help your organisation, fill in our contact form and a member of the team will get in touch.

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C/O Ampa Holdings Llp, Level 19, The Shard, 32 London Bridge Street, London SE1 9SG

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